XEOMIN is an effective drug that has been available by prescription since 2005, to treat pain in the head and neck pain symptoms that occur during Cervical Dystonia. It is also used to treat muscle spasms in the eyelid which is otherwise known as Blepharospasm. The Blepharospasm is usually an effect of Botox.
The Food and Drug Administration (FDA) has approved the supplemental Biologics License Application (sBLA) for Xeomin® (incobotulinumtoxinA; Merz Pharmaceuticals) for the treatment of chronic sialorrhea in patients aged 2 years and older. Previously, Xeomin was only approved for chronic sialorrhea in adults.
How does Xeomin work on muscles?
Once XEOMIN has been injected into the muscles, it starts to inhibit acetylcholine from being released. It is this chemical that makes fibers in the muscle contract, so without acetylcholine, muscles will contract less, resulting in fewer spasms and discomfort to the individual.
XEOMIN is an anti-wrinkle injection medicine: that is injected into muscles and used to:
- treat increased muscle stiffness in the arm because of upper limb spasticity in adults.
- treat increased muscle stiffness in the arm in children 2 to 17 years of age with upper limb spasticity, excluding spasticity caused by cerebral palsy.
- treat the abnormal head position and neck pain with cervical dystonia (CD) in adults.
- treat abnormal spasms of the eyelids (blepharospasm) in adults.
It is not known if XEOMIN is safe and effective in children younger than:
- 2 years of age for the treatment of chronic sialorrhea
- 2 years of age for the treatment of upper limb spasticity
- 18 years of age for the treatment of glabellar frown lines, cervical dystonia or blepharospasm
Spread of toxin effects: In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.